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BRL Abstracts Database |
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Your search for ultrasound produced 3296 results. Page 74 out of 330
| Title |
Continuous ultrasound and fetal movement. |
| Author |
Hertz RH, Timor-Tritsch I, Dierker LJ Jr, Chik L, Rosen MG. |
| Journal |
Am J Obstet Gynecol |
| Volume |
|
| Year |
1979 |
| Abstract |
No Abstract Available |
| Title |
Continuous wave measurements of acoustic attenuation in an oil/polymer mixture. |
| Author |
Fyke FE, Greenleaf JF, Johnson SA. |
| Journal |
Ultrasound Med Biol |
| Volume |
|
| Year |
1979 |
| Abstract |
No abstract available |
| Title |
Continuous wave ultrasound for non-invasive human arterial investigation. |
| Author |
Fitzgerald DE, Brew K, Webb CF. |
| Journal |
Technol Ireland |
| Volume |
|
| Year |
1973 |
| Abstract |
No abstract available. |
| Title |
Continuous-wave ultrasound and neoplastic transformation in vitro. |
| Author |
Harrison GH, Balcer-Kubiczek EK. |
| Journal |
Ultrasound Med Biol |
| Volume |
|
| Year |
1989 |
| Abstract |
C3H/10T1/2 cells in suspension were assayed using an initiation-promotion protocol for neoplastic transformation induced by continuous-wave ultrasound. Cells were insonated at 1.765 MHz for 40 min. Two ultrasonic intensities were used: 1.3 and 2.6 W/cm2 spatial average. The first intensity was found to be noncytotoxic; the second resulted in immediate lysis of 20% of the cells, followed by the clonogenic survival of 64% of the remaining cells. Ultrasound was delivered alone or in combination with X-rays (2 Gy, 240 kVp given before ultrasound), and/or 12-O-tetradecanoyl-phorbol-13-acetate (TPA, 0.1 microgram/ml post-irradiation). Under all treatment conditions, there was no effect of ultrasound on transformation at the 95% confidence level. |
| Title |
Contrast agent-induced cardiac arrhythmias in rats. |
| Author |
Zachary JF, Hartleben SA, Frizzell LA, O'Brien WD Jr. |
| Journal |
Proc Ultrason Symp IEEE |
| Volume |
|
| Year |
2001 |
| Abstract |
Although no known meaningful health risks have been reported following the use of microbubble ultrasound echogenic contrast imaging agents (MUECIA) in the United States, premature ventricular contractions have been documented in a report from the Netherlands and anecdotally noted in clinical use. Based on this information, we designed a study to characterize electrocardiogram conduction abnormalities in rat hearts exposed to pulsed ultrasound following injection of contrast agent. A focused 51-mm-diameter, 3.1-MHz, transducer that had in situ (at the heart) peak rarefactional and compressional pressures of 15.9 MPa and 36.1 MPa, respectively was used to expose each heart. ECGs were recorded digitally and continuously during seven experimental intervals: ECG baseline; exposure to pulsed ultrasound without intravenous MUECIA; discontinue ultrasound exposure and then inject intravenous MUECIA; expose to pulsed ultrasound with intravenous MUECIA; discontinue ultrasound exposure; exposure to pulsed ultrasound with intravenous MUECIA; and discontinue ultrasound exposure. Rats had no meaningful conduction abnormalities when exposed to ultrasound alone or contrast agent alone but developed premature atrial and ventricular complexes and polymorphic ventricular tachycardia when contrast agent was administered intravenously and the heart exposed to pulsed ultrasound. When ultrasound exposure was concluded, cardiac arrhythmias ceased but reoccurred when ultrasound exposure was resumed. Necrotic cardiac rhabdomyocytes were observed microscopically in myocardium of rats exposed to ultrasound following injection of contrast agent. Because cardiac arrhythmias were induced only when contrast agent interacted with ultrasound during exposure, the presence of myocardial lesions alone did not appear sufficient to serve as foci for ectopic electrical activity. These results suggest that microbubble contrast agent through its biomechanical interactions with pulsed ultrasound has the potential to induce conduction abnormalities leading to potentially hazardous cardiac arrhythmias. |
| Title |
Contrast agents and contrast imaging in ultrasound. |
| Author |
Ortman L. |
| Journal |
J Diagn Med Sonogr |
| Volume |
|
| Year |
2002 |
| Abstract |
This article reviews studies using ultrasound contrast agents and discusses several of the contrast agents currently available. The anatomical areas that are enhanced by contrast, examination, and techniques, are used in imaging with contrast agents. |
| Title |
Contrast agents for diagnostic ultrasound. |
| Author |
Ziskin MC, Bonakdarpour A, Weinstein DP, Lynch PR. |
| Journal |
Invest Radiol |
| Volume |
|
| Year |
1972 |
| Abstract |
A major advance in diagnostic ultrasound occurred with the discovery that indocyanine green completely opacifies the intraluminal areas of blood vessels and heart chambers on ultrasonic echograms containing these structures. Virtually any fluid if injected rapidly can produce this contrast effect, which is due to the production of cavitation bubbles. We evaluate here a number of agents as to their constrast efficiency. Ether, a fluid which boils vigorously at body temperature, was found to be the most effective contrast agent. |
| Title |
Contrast agents in diagnostic ultrasound. |
| Author |
Ophir J, Parker KJ. |
| Journal |
Ultrasound Med Biol |
| Volume |
|
| Year |
1989 |
| Abstract |
We review the field of contrast agents in diagnostic ultrasound. The progress in the development of various classes of contrast agents such as.free and encapsulated gas bubbles, colloidal suspensions, emulsions, and aqueous solutions is described. The mechanisms for production of.backscatter contrast, as well as attenuation contrast and speed of sound contrast are explained. Finally, the potential advantages and.disadvantages of various classes of contrast agents are compared. Published erratum appears in Ultrasound Med Biol 1990;16(2):209 . |
| Title |
Contrast echocardiography: new agents. |
| Author |
Miller AP, Nanda NC. |
| Journal |
Ultrasound Med Biol |
| Volume |
|
| Year |
2004 |
| Abstract |
In this report, we review the history, rationale, current status and future directions of previous termcontrast agentsnext term in previous termechocardiography.next term First, we discuss the historic development of previous termcontrast agentsnext term through a review of important physical principles of microbubbles in ultrasonography. Second, we identify attributes of an ideal previous termcontrast agentnext term and review those that are currently available or in the “pipeline” for clinical use. Third, we review indications for previous termcontrast echocardiography,next term including endocardial border detection, perfusion quantification and reperfusion assessment, and validate these observations by comparisons with other imaging modalities. Then, we briefly review different methodologies of performing a previous termcontrastnext term study, including interrupted, real-time and a hybrid modality. Finally, we identify novel future applications of the previous termnewest contrast agents. These newernext term concepts in previous termcontrast echocardiographynext term should form a foundation for nearly limitless application of previous termechocardiographynext term in improved anatomical assessment, perfusion imaging and even special applications, such as detection of vascular inflammation and site-specific drug delivery. |
| Title |
Contrast ultrasound imaging does not affect heat shock protein 70 expression in cholesterol-fed rabbit aorta |
| Author |
Smith BW, Simpson DG, Miller RJ, Erdman JW Jr, O'Brien WD Jr. |
| Journal |
J Ultrasound Med |
| Volume |
|
| Year |
2015 |
| Abstract |
Objectives—Diagnostic ultrasound imaging is enhanced by the use of circulating
microbubble contrast agents (UCAs), but the interactions between ultrasound, UCAs, and vascular tissue are not fully understood. We hypothesized that ultrasound with a UCA would stress the vascular tissue and increase levels of heat shock protein 70 (Hsp70), a cellular stress protein.
Methods—Male New Zealand White rabbits (n = 32) were fed a standard chow diet
(n = 4) or a 1% cholesterol, 10% fat, and 0.11% magnesium diet (n = 28). At 21 days, 24 rabbits on the cholesterol diet were either exposed to ultrasound (3.2-MHz f/3 transducer; 2.1 MPa; mechanical index, 1.17; 10 Hz pulse repetition frequency; 1.6 micro - seconds pulse duration; 2 minutes exposure duration at 4 sites along the aorta) with the UCA Definity (1× concentration, 1 mL/min; Lantheus Medical Imaging, North Billerica, MA) or sham exposed with a saline vehicle injection (n = 12 per group). Four rabbits on the cholesterol diet and 4 on the chow diet served as cage controls and were not exposed
to ultrasound or restrained for blood sample collection. Animals were euthanized 24 hours after exposure, and aortas were quickly isolated and frozen in liquid nitrogen. Aorta lysates from the area of ultrasound exposure were analyzed for Hsp70 level by Western blot. Blood plasma was analyzed for cholesterol, Hsp70, and von Willebrand factor, a marker of endothelial function.
Results—Plasma total cholesterol levels increased to an average of 705 mg/dL. Ultrasound did not affect plasma von Willebrand factor, plasma Hsp70, or aorta Hsp70. Restraint increased Hsp70 (P < .001, analysis of variance).
Conclusions—Restraint, but not ultrasound with the UCA or cholesterol feeding,
significantly increased Hsp70.
Key Words—atherosclerosis; cardiovascular disease; contrast agents; endothelium;
heat shock protein 70; microbubbles; ultrasound |
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