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BRL Abstracts Database |
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Your search for ultrasound produced 3296 results. Page 282 out of 330
| Title |
Transnasal US of the esophagus: Preliminary morphologic and function studies. |
| Author |
Liu JB, Miller LS, Goldberg BB, Feld RI, Alexander AA, Needleman L, Castell DO, Klenn PJ, Millward CL. |
| Journal |
Radiology |
| Volume |
|
| Year |
1992 |
| Abstract |
High-frequency catheter-based ultrasound (US) transducers can be inserted into the esophagus transnasally to evaluate esophageal wall structures. Studies were performed in two sheep esophagus specimens in vitro, in 17 healthy human subjects, and in 16 patients with esophageal abnormalities (eight with achalasia, four with scleroderma, three with esophageal carcinoma, and one with esophagitis). In the sheep specimens, endoluminal US delineated seven layers of the esophageal wall; these results correlated closely with histologic findings. Real-time US of the normal esophageal wall was performed during resting and swallowing. Muscles at the lower esophageal sphincter (LES) were shown to be thicker than muscles in the body the esophagus. Thickening of the muscular layers at the LES in achalasia, dilated blood vessels within the submucosa in esophagitis, and fibrotic changes within the muscular layers in scleroderma were demonstrated. Extramural structures adjacent to the esophagus were also seen. These preliminary results suggest that transnasal esophageal US may become an important diagnostic tool in evaluation of the esophagus. |
| Title |
Transplant immunity in hamsters treated with ultrasound. |
| Author |
Hare JD, Linke CA, Child SZ, Fridd CW, Carstensen EL, Davis HT. |
| Journal |
J Clin Ultrasound |
| Volume |
|
| Year |
1982 |
| Abstract |
Hamsters with subcutaneous fibrosarcomas were treated by excision and by exposure to 5-MHz ultrasound for six minutes at an intensity of 3 W/sq cm. Rates for successful elimination of the tumors were between 80% and 90% and were not significantly different for the two methods of treatment. After 30 days, the animals were challenged with the same tumor cells. Animals successfully treated with ultrasound or excision required at least 10 times as many cells to produce a tumor as controls, indicating that eradication of the tumor by ultrasound induced a level of transplant immunity at least as good as that resulting from surgical excision. |
| Title |
Transrectal ablation of prostate tissue using focused ultrasound. |
| Author |
Snaghvi NT, Foster RS, Bihrle R, Fry FJ, Phillips M, Hennige C. |
| Journal |
Proc Ultrason Symp IEEE |
| Volume |
|
| Year |
1993 |
| Abstract |
Canine and human prostates were treated with high intensity focused ultrasound (HIFU) using a transrectal probe. Near the beam focus, temperatures were shown to be greater than 60°C, while periprostatic tissue temperatures increased ⩽3°C; rectal wall temperatures did not rise more than 5°C over the baseline. In 15 patients with benign prostatic hyperplasia (BPH), no major complications resulted from HIFU treatment, and statistically significant improvements in peak and average flow rates were observed at both 90 and 180 days post-treatment |
| Title |
Transrectal ultrasound for monitoring murine orthotopic prostate tumor. |
| Author |
Kusaka N, Nasu Y, Arata R, Saika T, Tsushima T, Kraaij R, Bangma CH, Kumon H. |
| Journal |
Prostate |
| Volume |
|
| Year |
2001 |
| Abstract |
BACKGROUND:
The mouse orthotopic prostate tumor model has been recognized as an ideal preclinical animal model simulating the anatomical and biological milieu of the prostate. In comparison with the subcutaneous tumor model, the only disadvantage of this model is the difficulty of chronological tumor growth monitoring. We have applied recent endoluminal ultrasound technology, transrectal ultrasonography (TRUS), to the monitoring of mouse orthotopic prostate tumors.
METHODS:
A 6 Fr. 20 MHz catheter-based radial scan probe was used and TRUS was performed without any prior preparation including anesthesia. Orthotopic tumors were initiated by inoculation of 5000 RM-9 cells into the dorsal prostate of 12-week-old C57BL/6 male mice. The tumor growth was monitored by TRUS from day 3 to day 21. In addition, TRUS was performed to detect tumor growth suppression after intraperitoneal administration of cis-diamminedichloroplatinum (CDDP).
RESULTS:
By ultrasound, tumors became detectable 7 days after tumor cell inoculation. TRUS images were clear and parallel to actual tumor growth. The tumor volume (X) calculated by TRUS correlated significantly with the actual tumor weight (Y) measured at autopsy; Y = 101.653 + 1.174X (R = 0.930, P < 0.001). Similarly, tumor growth suppression induced by CDDP was clearly detected by TRUS with reasonable accuracy.
CONCLUSIONS:
A high resolution TRUS allows simple and reliable monitoring of in situ tumor growth and growth suppression, making the mouse orthotopic prostate tumor model more efficient. |
| Title |
Transthoracic cardiac ultrasonic stimulation induced a negative chronotropic effect. |
| Author |
Buiochi EB, Miller RJ, Hartman E, Buiochi F, Bassani RA, Costa ET, O'Brien WD Jr. |
| Journal |
IEEE Trans UFFC |
| Volume |
|
| Year |
2012 |
| Abstract |
The objective of this study is to investigate cardiac bioeffects resulting from ultrasonic stimulation using a specific set of acoustical parameters. Ten Sprague–Dawley rats were anesthetized and exposed to 1-MHz ultrasound pulses of 3-MPa peak rarefactional pressure and approximately 1% duty factor. The pulse repetition frequency started slightly above the heart rate and was decreased by 1 Hz every 10 s, for a total exposure duration of 30 s. The control group was composed of five rats. Two-way analysis of variance for repeated measures and Bonferroni post hoc tests were used to compare heart rate and ejection fraction, which was used as an index of myocardial contractility. It was demonstrated for the first time that transthoracic ultrasound has the potential to decrease the
heart rate by ~20%. The negative chronotropic effect lasted for at least 15 min after ultrasound exposure and there was no apparent gross damage to the cardiac tissue. |
| Title |
Transurethral high intensity focused ultrasound: catheter based prototypes and experimental results. |
| Author |
Seip R, Biswas M, Kuznetsov M, Sanghvi NT. |
| Journal |
UFFC |
| Volume |
|
| Year |
2000 |
| Abstract |
Transurethral catheters containing multiple high-intensity focused ultrasound (HIFU) transducers at their tip have been designed, built and tested for the
treatment of prostate tissue. These catheters address a need in the medical community for simple, fast, and effective treatments using low-cost, disposable, and application-specific devices for disease control through tissue ablation. The HIFU transducers used in the transurethral catheter prototypes have a focal
length of 10 mm, operate at 5 MHz, and are able to generate total acoustic power levels exceeding 8 Watts. Experimental in vitro and in vivo results show that the catheters can ablate cylindrical tissue volumes > 5 cm3 around the urethra in less than 15 minutes through simple catheter rotation. These results indicate that catheter-based HIFU transducers can be used to provide a viable alternative to current minimally-invasive therapies for prostate diseases, such as BPH. The technologies also show promise for the treatment of other diseases that would benefit from using small, minimally invasive HIFU transducers (such as esophageal, thoracic, and ear/nose/throat and OB/Gyn applications). Catheter
prototypes are described, and in vitro,in vivo,and histology data are presented. |
| Title |
Treating spontaneous tumors in dogs and cats by ultrasound-induced hyperthermia. |
| Author |
Marmor JB, Pounds D, Hahn N, Hahn GM. |
| Journal |
Int J Radiat Oncol Biol Phys |
| Volume |
|
| Year |
1978 |
| Abstract |
No abstract available. |
| Title |
Treatment of experimental lens capsular tears with intense focused ultrasound. |
| Author |
Coleman DJ, Lizzi FL, Torpey JH, Burgess SE, Driller J, Rosado A, Nguyen HT. |
| Journal |
Br J Ophthalmol |
| Volume |
|
| Year |
1985 |
| Abstract |
High-intensity focused ultrasound was employed to seal lens capsular tears in a rabbit model. Ultrasound therapy was applied either contiguously, thereby completely covering the tear, or in a discrete exposure pattern around the tear. Both methods prevented the formation of a generalised cataract. This was in contrast to results observed in a group of control (untreated) animals which all developed generalised lens opacities. Each control animal also developed a local lens opacity at the site of the capsular tear, as did half the animals treated with the discrete pattern. No animal treated with contiguous exposures developed any local or generalised traumatic-type cataract other than the small lens opacity immediately produced by the treatment. These treatment cataracts would not constitute a significant impediment to vision so long as they did not fall on the visual axis.
|
| Title |
Treatment of genital herpes simplex virus in male patients. |
| Author |
Fahim MS, Brawner TA. |
| Journal |
Arch Androl |
| Volume |
|
| Year |
1980 |
| Abstract |
Twenty-three male patients with herpes simplex virus type 2 blisters on the prepuce, glans penis, and penile. shaft were divided into 2 groups. Ten patients served as controls, and thirteen patients were treated with. ultrasound (1 W/cm2 for 60 sec) and Herpigon on 3 consecutive days. Results showed a negative virus culture. after 3 days of treatment and significant reduction of the recurrent infection in the treated group while the. control group experienced recurrent infection within 62--80 days. This method offers a new therapeutic. treatment for genital herpes simplex virus. |
| Title |
Treatment of glaucoma with high-intensity focused ultrasound. |
| Author |
Burgess SE, Silverman RH, Coleman DJ, Yablonski ME, Lizzi FL, Driller J, Rosado A, Dennis JR PH. |
| Journal |
Ophthalmology |
| Volume |
|
| Year |
1986 |
| Abstract |
This report is a summary of results for 170 eyes of patients with refractory glaucoma treated with high-intensity focused ultrasound. The results are analyzed in terms of the effectiveness of various treatment regimens, complications, and classifications of the patient population according to such factors as age and etiology. The mean pretreatment intraocular pressure (IOP) for the ensemble of patients treated with optimal intensity levels was 38.6 mmHg. Whereas only 10% of these patients had an IOP of 25 mmHg or less prior to treatment, 90% had an IOP of 25 mmHg or less within 3 months of treatment. At 1 year after a single treatment, 65% of patients still maintained intraocular pressures of 25 mmHg or less, and 56% had pressures of 22 mmHg or less. The effectiveness of retreatment of failed or unresponsive cases was also investigated and found to have a degree of success comparable to that of initial treatments. |
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