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BRL Abstracts Database |
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Your search for ultrasound produced 3296 results. Page 214 out of 330
| Title |
Radionuclide tumour therapy with ultrasound contrast microbubbles. |
| Author |
van Wamel A, Bouakaz A, Bernard B, ten Cate F, de Jong N. |
| Journal |
Ultrasonics |
| Volume |
|
| Year |
2004 |
| Abstract |
Radionuclides have shown to be effective in tumour therapy. However, the side effects determine the maximum deliverable dose. Recently, it has been demonstrated that cells can be permeabilised through sonoporation using ultrasound and contrast microbubbles. The use of sonoporation in treatment of tumours may increase the anti-tumour efficacy of radionuclide treatment. The mechanisms as well as the effects sonoporation in tumour treatment strategies are still not understood. The purpose of this study is to determine the effects of ultrasound and contrast microbubbles on the internalisation of the radionuclide 111In-DOTA-Tyr3-octreotate in tumour cells. To optimize ultrasound settings for ultrasound adjunctive tumour therapy we incubated rat pancreatic CA20948 tumour cells with two dyes (MW 40 and 70 kDa). The uptake levels were compared with cells treated with ultrasound and contrast microbubbles for different ultrasound settings. The highest molecular uptake was found with addition of contrast microbubbles (ratio of 10 bubbles to 1 cell) and with the ultrasound setting: duty cycle 0.013%, mechanical index (MI) 0.42, and treatment times of 30 and 60 min. These settings were used to enhance the internalisation of 111In-DOTA-Tyr3-octreotate. We found a 160% higher internalisation of 111In-DOTA-Tyr3-octreotate by tumour cells adjunctively treated with ultrasound and contrast microbubbles compared to untreated cells. These results show that adjunctive tumour treatment with the radionuclide 111In-DOTA-Tyr3-octreotate and ultrasound contrast microbubbles may be feasible. When using adjunctive ultrasound contrast microbubble treatment, a lower radionuclide doses are required to reach the same anti-tumour effect. |
| Title |
Rapid evaluation of many pulse echo system characteristics by use of a triggered pulse burst generator with exponential decay. |
| Author |
Carson PL. |
| Journal |
J Clin Ultrasound |
| Volume |
|
| Year |
1976 |
| Abstract |
A pulse burst generator is utilized in which the pulses are triggered by the transmitter pulse of the ultrasound system being tested. The pulses are spaced the equivalent of every 2 mm in the body, and their amplitude decays with 0, 1.25, or 2.5 dB/cm over greater than a 50 dB dynamic range. By replacing the ultrasound transducer with the pulse generator, one can record quite easily the accuracy of depth gain compensation (DGC) and of distance measurements in A mode and B mode. If the DGC on the ultrasound unit can be turned to zero, the unit's A mode display characteristic and B mode gray scale curve can be determined rapidly and the receiver gain control or attenuator can be calibrated. Measurement of a receiver signal-to-noise ratio is possible, and more quantitative imaging should be facilitated as well. |
| Title |
Rapid ultrasound scanning of both breasts positioned and compressed in the mode of x-ray mammography. |
| Author |
Kelly-Fry E. |
| Journal |
J Ultrasound Med |
| Volume |
|
| Year |
1994 |
| Abstract |
No abstract available. |
| Title |
Rationale and derivation of MI and TI--a review. |
| Author |
Abbott JG. |
| Journal |
Ultrasound Med Biol |
| Volume |
|
| Year |
1999 |
| Abstract |
This review article provides a summary rationale and derivation for the mechanical index (MI) and thermal index (TI) formulas.presented in the body of the "Standard for real-time display of thermal and mechanical acoustic output indices on diagnostic.ultrasound equipment" (AIUM/NEMA 1998). For purposes of simplicity, this standard is referred to in this article by its colloquial "nickname," the "output display standard" or ODS. This review expands on the summary information provided in Appendix A of the ODS. Numerous references are made to the root publications from which the formulas were derived. As will be discussed in the derivation notes that follow, key parts of the MI and TI models rely heavily on experimental data. This document does not attempt to do any more than describe the relevant results of the experiments. A general overview is provided in the Introduction and Rationale for the nontechnical reader and the more rigorous Models and Derivation Notes provides a detailed mathematical review of the MI and TI models. A complete set of defined terms is provided in Appendix 1. |
| Title |
Real time measurement system of velocity profile in human body by pulsive ultrasound echo. |
| Author |
Okujima M, Ohtsuki S, Kuzuya K. |
| Journal |
Proc JSUM |
| Volume |
|
| Year |
1982 |
| Abstract |
We developed a velocity profile measuring method, where the velocity of reflective body were measured from the time shift of its echo. The system based on this method enables high speed processing and real time display of velocity profile. In the realized system, echo signals were sampled into one-bit digital signals, and then compared with corresponding signals sampled one repetition time before. It was examined successfully with moving target model in water, and then applied to the observation of velocity profile in human body... |
| Title |
Real time pelvic ultrasonography during the periovulatory period of patients attending an artificial insemination clinic. |
| Author |
Marinho AO, Sallam HN, Goessens LK, Collins WP, Rodeck CH, Campbell S. |
| Journal |
Fertil Steril |
| Volume |
|
| Year |
1982 |
| Abstract |
Real time ultrasonography was used to examine the ovaries of 50 patients at the calculated time for artificial insemination with donor semen (AID). Forty-two (84%) had one or more follicles greater than 13 mm in diameter. Both ovaries were monitored daily until the main follicle had ruptured (mean number of examinations, 2.4 per patient; range, 1 to 5). Seven women became pregnant (mean follicular diameter, 21.6 mm; range, 18 to 25 mm). The fecundability rate was 12%, compared with 6% for a corresponding group of 50 patients who were not examined with.ultrasound. Seven patients experienced mittelschmerz, and in 39 the leading follicle had ruptured before the rise in basal body temperature (BBT). Ultrasonography may be used to confirm the presence or absence of preovulatory follicle prior to treatment. |
| Title |
Real time two dimensional ultrasound imaging. |
| Author |
von Ramm OT. |
| Journal |
Proc Sixth N Engl Bioeng Conf |
| Volume |
|
| Year |
1978. |
| Abstract |
No abstract available. |
| Title |
Real time ultrasound abdominal imaging. |
| Author |
Johnson ML, von Ramm OT, Kisslo JA, Thurstone FL. |
| Journal |
Proc Twentieth Annu Meet AIUM |
| Volume |
|
| Year |
1975 |
| Abstract |
No abstract available. |
| Title |
Real time ultrasound tomography of the adult brain. |
| Author |
Smith SW, von Ramm OT, Kisslo JA, Thurstone FL. |
| Journal |
Stroke |
| Volume |
|
| Year |
1978 |
| Abstract |
Initial clinical results are reported from a new real time, 2-dimensional ultrasound scanner modified for adult cephalic applications. An optimized transducer design and the use of the dynamically focused phased array imaging system have resulted in ultrasound tomograms of the brain which are significant improvements over previous attempts. Horizontal and coronal images of the ventricles, the corpus callosum and other midline structures are rountinely displayed in a 45? sector format. In addition, pulsating cerebral arteries are displayed in real time. Quantitative information can be obtained concerning cerebral vascular patency by using the selectable M-mode feature of this system. The results indicate that real time ultrasound tomography has potential for clinical application. |
| Title |
Real-time calculation of a limiting form of the renyi entropy applied to detection of subtle changes in scattering architecture. |
| Author |
Hughes MS,McCarthy Mc,Wickerhauser MV,Marsh JN,Arbeit JM,Fuhrhop RW,Wallace KD,Thomas T,Smith J,Agyem K,Lanza GM,Wickline SA. |
| Journal |
J Acoust Soc Am |
| Volume |
|
| Year |
2009 |
| Abstract |
Previously a new method for ultrasound signal characterization using entropy Hf was reported, and it was demonstrated that in certain settings, further improvements in signal characterization could be obtained by generalizing to Renyi entropy-based signal characterization If(r)with values of r near 2 (specifically r=1.99) (M. S. Hughes et al., J. Acoust. Soc. Am. 125, 3141–3145 (2009)). It was speculated that further improvements in sensitivity might be realized at the limit r→2. At that time,such investigation was not feasible due to excessive computational time required to calculate If(r) near this limit. In this paper, an asymptotic expression for the limiting behavior of If(r) as r→2 is
derived and used to present results analogous to those obtained with If(1.99). Moreover, the limiting form If,∞ is computable directly from the experimentally measured waveform f(t) by an algorithm
that is suitable for real-time calculation and implementation. |
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