Bioacoustics Research Lab
University of Illinois at Urbana-Champaign | Department of Electrical and Computer Engineering | Department of Bioengineering
Department of Statistics | Coordinated Science Laboratory | Beckman Institute | Food Science and Human Nutrition | Division of Nutritional Sciences | College of Engineering
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Your search for ultrasound produced 3296 results.

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Title Premature ventricular contractions during triggered imaging with ultrasound contrast.
Author van Der Wouw PA, Brauns AC, Bailey SE, Powers JE, Wilde AA.
Journal J Am Soc Echocardiogr
Volume
Year 2000
Abstract BACKGROUND: Premature ventricular contractions (PVCs) were observed during triggered second harmonic imaging of a contrast agent for myocardial perfusion assessment, with continuous infusion of the contrast agent. Further investigation into the relation of this phenomenon to both ultrasound energy and the contrast agent was carried out during a subsequent bolus-versus-infusion study. METHODS AND RESULTS: Two open-label studies in healthy male volunteers were performed. The initial study was a dose-response study in 10 subjects, which compared 3 infusion rates. Each volunteer received 3 continuous infusions with different infusion rates of the contrast agent for either 10 (n = 6) or 20 (n = 4) minutes. End-systolic triggered imaging with a mechanical index (MI) of 1.5 was used throughout this part of the study. The second study compared bolus injection with a continuous infusion in 9 volunteers, with a single-dose level but different imaging modalities: end-systolic and end-diastolic triggered imaging at MIs of both 1.1 and 1.5. Spontaneous baseline PVCs were uncommon: 10 in 344 minutes (0.03 PVC/min, maximal 1 PVC/min) of baseline imaging. During end-diastolic triggering, no increase in PVCs was seen, irrespective of MI. A significant increase to 1.06 PVC/min (P <.001) was seen during end-systolic imaging with an MI of 1.5, but not with an MI of 1.1. The increase in PVC rate was dose-dependent in the initial study. CONCLUSION: Imaging of contrast agents with high acoustic pressures can cause PVCs if end-systolic triggering is used. This effect is related to both the dose of contrast agent and acoustic pressure. It does not occur during end-diastolic triggered imaging. Precautionary measures would include using lower MIs or end-diastolic triggering..


Title Prenatal application of diagnostic ultrasound in mice.
Author Hrazdira I, Sulcova A, Kellnerova R, Huskova B.
Journal Ultrasound Med Biol
Volume
Year 1995
Abstract No abstract available.


Title Prenatal diagnosis of neural tube defects: origin of midtrimester vertebral ossification centers as determined by sonographic water-bath studies.
Author Gray DL, Crane JP, Rudloff MA.
Journal J Ultrasound Med
Volume
Year 1988
Abstract A normal vertebral column was removed from a 17-week stillborn fetus and suspended in a water bath. The specimen was sequentially dissected, with spinous processes, transverse processes, and remaining neural arch removed. After dissection, each specimen was imaged by ultrasound in axial, sagittal, and coronal planes. The resultant images clearly demonstrated the origin of the three ossification centers as one at each lamina-pedicle junction and one in the.vertebral body. Corollary X-ray studies confirmed the ultrasound findings and, in a case of open spina bifida, demonstrated the superiority of sonography for making this diagnosis.


Title Prenatal exposure to ultrasound waves impacts neuronal migration in mice.
Author Ang ES Jr, Gluncic V, Duque A, Schafer ME, Rakic P.
Journal Proc Natl Acad Sci USA
Volume
Year 2006
Abstract Neurons of the cerebral neocortex in mammals, including humans, are generated during fetal life in the proliferative zones and then migrate to their final destinations by following an inside-to-outside sequence. The present study examined the effect of ultrasound waves (USW) on neuronal position within the embryonic cerebral cortex in mice. We used a single BrdU injection to label neurons generated at embryonic day 16 and destined for the superficial cortical layers. Our analysis of over 335 animals reveals that, when exposed to USW for a total of 30 min or longer during the period of their migration, a small but statistically significant number of neurons fail to acquire their proper position and remain scattered within inappropriate cortical layers and/or in the subjacent white matter. The magnitude of dispersion of labeled neurons was variable but systematically increased with duration of exposure to USW. These results call for a further investigation in larger and slower-developing brains of non-human primates and continued scrutiny of unnecessarily long prenatal ultrasound exposure.


Title Presence of cepstral peak in random reflected ultrasound signals.
Author Kuc R, Haghkerdar K, O'Donnell M.
Journal Ultrason Imaging
Volume
Year 1986
Abstract A peak in the power cepstrum, or the squared magnitude of the Fourier transform of the data log-power spectrum, is commonly observed when processing reflections from plate-like structures, such as membranes. In this case, the cepstral peak at the smallest nonzero time lag, or quefrency, value can be used to determine the thickness of the plate. For reflections from a medium composed of randomly distributed scatterers, such as liver tissue, a cepstral peak is also commonly observed, but cannot be so intuitively explained as in the deterministic case above. In this paper, it is demonstrated that the presence of a cepstral peak depends on the form of the probability density function (pdf) of the separation between reflectors. In the case where the pdf is uniform from O to SM, the cepstral peak is found to occur at the quefrency corresponding to SM. For simple unimodal pdfs, a cepstral peak will occur at the location of the maximum probability. These observations are shown.analytically and verified through simulations. The diagnostic value of these results lies in the interpretation of the relation of the cepstral peak location to the spacing of the scattering elements in the tissue.


Title Present and future applications of ultrasonics in biomedicine.
Author Fry WJ.
Journal Proc IRE
Volume
Year 1962
Abstract The current importance of ultrasonic energy for the investigation and modification of biological systems is reviewed and the immediately foreseeable potential apparent to the author is predicted. The uses of ultrasound in basic research studies of biological systems and medical applications are conveniently grouped into two major categories: passive uses, or those in which the acoustic field does not significantly modify either permanently or temporarily structure and/or function of the system, and active uses, or those in which modification of the system is the objective. Included within the first category are: absorption spectroscopy of solutions of macromolecular species, microscopy of cells and tissues, absorption characteristics of gross tissue, and visualization of soft tissue structure and its dynamics. The second category includes: the use of ultrasound in neuroanatomical and neurophysiological studies and the treatment of neurological disorders by the production of selective permanent or temporary changes in arrays of sites in the central nervous system, destruction of carcinogenic tissue, modification of endocrine glands, investigation of contractile and other properties of muscle, and the potentiation of ionizing radiation by simultaneous application of ultrasound. Applications of ultrasound in the biomedical field of a primarily technological nature are either mentioned only briefly or omitted entirely from the review. The "socioeconomic" factors which determine the level of financial support, and thus the rate of scientific progress, for a field are also briefly mentioned.


Title Present and future technology for simultaneous superficial thermoradiotherapy of breast cancer.
Author Moros EG,Peňagarciano J,Novàk P,Straube WL,Myerson RJ.
Journal Int J Hyperthermia
Volume
Year 2010
Abstract This paper reviews systems and techniques to deliver simultaneous thermoradiotherapy of breast cancer. It first covers the clinical implementation of simultaneous delivery of superficial (microwave or ultrasound) hyperthermia and external photon beam radiotherapy, first using a Cobalt-60 teletherapy unit and later medical linear accelerators. The parallel development and related studies of the Scanning Ultrasound Reflector Linear Arrays System (SURLAS), an advanced system specifically designed and developed for simultaneous thermoradiotherapy, follows. The performance characteristics of the SURLAS are reviewed and power limitation problems at high acoustic frequencies (>3 MHz) are discussed along with potential solutions. Next, the feasibility of simultaneous SURLAS hyperthermia and intensity modulated radiation therapy/image-guided radiotherapy (IMRT/IGRT) is established based on published and newly presented studies. Finally, based on the encouraging clinical results thus far, it is concluded that new trials employing the latest technologies are warranted along with further developments in treatment planning.


Title Present highlights of ultrasound in medicine.
Author Buschmann HW.
Journal Dig Seventh Int Conf Med Biol Eng - Stockholm
Volume
Year 1967
Abstract No abstract available.


Title Present state of an ultrasonic cross-section procedure with rapid image rate.
Author Patzold J, Krause W, Kresse H, Soldner R.
Journal IEEE Trans Biomed Eng
Volume
Year 1970
Abstract The scan unit attains a rapid-image rate by rotating the sound source at a frequency of about 16 Hz in the focal point of an acoustic cylindrical paraboloid mirror. By this arrangement a scanning beam is obtained that moves with a speed of about 2 m/s transverse to the direction of propagation of the ultrasound. This scanning speed permits the buildup of a sectional image within about 60 ms with an image frequency of about 16 Hz. As the scanning procedure is automatic and not manual, a high degree of objectivity is obtained with respect to imaging of contours and particularly of inhomogeneous tissues. The above-mentioned image frequency also permits visualization of kinetic processes inside the body; these can be viewed on the fluorescent screen or filmed. Finally, the properties and limits of ultrasonic imaging are dealt with in comparison with radiography.


Title Present status of ultrasound hyperthermia.
Author Hynynen K.
Journal Proc Ultrason Symp IEEE
Volume
Year 1988
Abstract The current ultrasound techniques for inducing elevated temperatures in malignant tumors are reviewed. Emphasis is placed on the mechanically scanned and focused systems that are presently under clinical evaluation. Some of the clinical results are reviewed, and the potential and limitations of ultrasound as a clinical tool for hyperthermia induction are evaluated on the basis of clinical experience. In addition, some of the future technical possibilities are discussed.


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